Summary of toxicity research

Summary of toxicity research

Research location: Republican Unitary Enterprise «Scientific and Practical Center of Hygiene» / Minsk / Republic of Belarus (M.V. Anisovich, E.S. Yurkevich)

Aim of the study: To investigate the toxicological properties and safety of Nanoplant.

Objects of the research: microfertilizer “Nanoplant” of various brands based on biopolymer-stabilized colloidal solutions of nanoparticles of microelements (Co, Mn, Cu, Fe, Zn, Cr, Se, Mo, Ag in various combinations and concentrations).

Developer: Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus / Minsk / Republic of Belarus (S.G. Azizbekyan)

Performed research:

Plant seed phytotoxicity – phytotoxicity not determined.

Acute Toxicity – no symptoms of intoxication

No cumulative properties – no symptoms of intoxication.

Immunotoxicity and susceptibility to epithelial tissue (skin) – no irritant effect.

DL50 (single-celled Tetrahymena pyriformis) – parameters of membrane toxicity, population growth models, growth rate, time and number of generations, population size, adaptogenicity. DL50 (after 3 and 24 hour exposure) was found to be greater than 1000 mg / ml. Tetrahymena pyriformis has not been shown to be toxic in the course of the study.

Ecotoxicity to the aquatic environment – no evidence of toxicity and genotoxicity.

Reproductive toxicity – no evidence of poisoning.

Conclusion: In accordance with Regulation (EC) No. The extended toxicological test for CLP 1272/2008 (CLP Regulation) found that all types of micro-nutrient fertilizers “Nanoplant” are non-toxic, non-ecotoxic and phytotoxic, do not cause long-term effects (mutagenicity, genotoxicity, reproductive effects).


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